Presenter: Caroline Mauvezin (University of Barcelona, Spain)
When: Friday 22nd May 2026, 10:00-11:00
Where: Radium Hospital LU1 auditorium, followed by cake and coffee/tea.
On Friday 22nd May, ARCTiC will have the great pleasure of hosting Dr. Caroline Mauvezin to present a Visiting Scientist seminar. Dr. Mauvezin is a group leader at the University of Barcelona (Spain), where she investigates the role of autophagy in cell division and cancer.
Dr. Caroline Mauvezin received her B.Sc. and M.Sc. training in Montpellier, France, followed by graduate studies in Barcelona, Spain. She earned her Ph.D. at IRB Barcelona in the laboratory of Dr. Antonio Zorzano, where she uncovered a previously unrecognized function of the nuclear co‑factor TP53INP2/DOR as an activator of autophagy, opening new conceptual avenues in the field.
She pursued postdoctoral training in Dr. Thomas Neufeld’s laboratory at the University of Minnesota (USA), where she resolved a long‑standing controversy by demonstrating that lysosomal acidification is not required for autophagosome–lysosome fusion, and identified a lipid‑interacting protein complex essential for accurate autophagic flux.
As a senior postdoctoral fellow at IDIBELL (Spain), supported by competitive fellowships, she investigated the role of lysosomes in E2F1‑induced mTOR activation and, later, the function of autophagy during mitosis. This work revealed that efficient autophagy safeguards chromosomal stability in cancer cells and introduced the toroidal nucleus as a novel cancer biomarker.
Dr. Mauvezin now leads a research group in the Department of Biomedicine at the University of Barcelona, focused on exploiting autophagy modulation as a therapeutic strategy in cancer. She is an active member of several autophagy networks, including SEFAGIA and Women in Autophagy.